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Mitochondrial fusion, fission, and cristae remodeling as key mediators of cellular function

Details and References: Coffee melanoidins may act as soluble fiber enhancing immune-stimulating properties and contributing significantly to reducing the risk of colon cancer (Vitaglione, 2012

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However, intraorally, hyperpigmentation is more typically a consequence of physiologic, idiopathic sources, neoplasia, medications, high serum concentrations of pituitary adrenocorticotropic hormone (ACTH), postinflammatory changes, and genetic or autoimmune disorders

doi: 10.3389/fimmu.2022.934695 112 RoopchandD.CarmodyR