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As the condition worsens, common symptoms include: weakness and fatigue light-headedness and dizziness palpitations and rapid heartbeat shortness of breath a sore tongue that has a red, beefy appearance nausea or poor appetite weight loss diarrhea yellowish tinge to the skin and eyes

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It inhibits NNMT, an enzyme that methylates nicotinamide (a precursor to NAD+)

Seek help immediately if you are experiencing any of the signs of vitamin B12 deficiency mentioned above

If you're getting a cyanocobalamin (also present in oral and sublingual B12) that's more likely to cause negative reactions

Haematological responses typically occur within 1-2 weeks, but neurological recovery may take months and can be incomplete if the deficiency has been prolonged