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A systematic review of the clinical use of Withania somnifera (Ashwagandha) to ameliorate cognitive dysfunction

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C-ABL Inhibitors So far trials with Abelson murine leukaemia viral oncogene homologue 1 (c-ABL) kinase inhibitors have not been successful with two randomised placebo-controlled trials with nilitonib and vodobatinib both failing to detect efficacy signals on the change from baseline of MDS-UPDRS part III scores [203]