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Our identification of VRK2-mediated SLC7A11 trafficking suggests a potential immune evasion mechanism, as SLC7A11-high tumors often display T cell exclusion phenotypes [37], warranting future investigation into whether VRK2 expression could predict therapeutic response to combined ferroptosis inducers and immune checkpoint inhibitors
[DOI] [PubMed] [Google Scholar] 44.Ruknuddin G., Basavaiah R., Biswajyoti P., Krishnaiah A., Kumar P
J Biol Chem 1993;268:196505.ArticlePubMed 36
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Exosomes: diagnostic biomarkers and therapeutic delivery vehicles for cancer
10.1021/jm060960h 43 DengS.-H.WuD.-M.LiL.LiuT.ZhangT.LiJ.et al (2021)
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