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The cAMP/CREB/BDNF is a crucial signaling pathway in regulating hippocampal neuronal regeneration in depression (Yamada et al., 2003)

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After 3 h of EV incubation, the number of incorporated Halo-Rac1 molecules per recipient cell, as measured by ELISA, was 5.5 3.0 10 4 (Fig