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At the cellular and structural level, evidence exists for a negative influence of NSAIDs on the muscle stem cell population (satellite cells) and on muscle connective tissues significant remodeling during muscle regeneration [85]

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In the published Phase I dose-escalation study in healthy adults, CJC-1295 with DAC showed good tolerability, with injection-site reactions reported as the most common adverse effect

doi:10.3389/fvets.2023.1082102

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