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However, excessive use or improper formulation can increase the risk of copper toxicity and adverse reactions

In some cases, increased vitamin C can result in kidney stones or even hemodialysis in people who are G6PD-deficient (a disease in which some drugs cause red blood cells to break down)

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Conversely, increasing the Bacteroidetes to Firmicutes ratio through high intake of dietary fiber may reduce caloric extraction from the diet and support weight loss (76)