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Introduction Nausea is the number one reason people consider stopping their GLP1 medication, and it is the most commonly reported side effect across semaglutide (Ozempic, Wegovy) and tirzepatide (Mounjaro, Zepbound)
Genetic predispositionssuch as variants in GIPR, GLP1R, MC4R, and FTO pathwaysrelate to appetite regulation and nutrient partitioning
doi: 10.1210/clinem/dgaf278 181 MartinCKCarmichaelOTCarnellSConsidineRVKarekenDADydakUet al