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For patients who prefer oral over injectable medications Contrave is a tablet taken twice daily, making it a practical alternative for patients who are uncomfortable with or unable to use weekly injections

Kidney function tests , including serum creatinine, estimated glomerular filtration rate (eGFR), and urine albumin-to-creatinine ratio (UACR), warrant attention

The goal is to increase the dose gradually until the highest tolerable dose (a dose that reaches the desired effect without unacceptable side effects) is reached

GLP-1 therapy creates the deficit

Without adequate vitamin D, calcium absorption drops to roughly 10-15% of dietary intake compared to 30-40% with sufficient levels

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