A meta-analysis reported an association between the pre-pregnancy maternal use of antidepressants and ASD in offspring and not during pregnancy (23)
Zuraikat goes further, suggesting that while the drugs can result in some physical symptoms of satiety, such as nausea, they are more potently driving the neural control of food intake. How do GLP-1 drugs alter tastes
Body Weight (Does It Matter?) For most peptides, dosage is not based on body weight in the same way as traditional pharmaceuticals
AACE/ACE 2023 obesity algorithm
Transdermal delivery offers the advantage of bypassing the first-pass effect in the liver, which may improve bioavailability compared to oral administration
Maintenance phase: Once the loading phase is complete, patients transition to maintenance therapy with 1 mg hydroxocobalamin intramuscularly every two to three months for life