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Forest plot of Lixisenatide versus comparators on the risk of overall Respiratory diseases

Clinical studies show that many individuals begin to see measurable weight loss within four to eight weeks of starting GLP-1 injections

IDO1, indoleamine 2, 3-dioxygenase 1

Lack of improvement after six months may indicate need for protocol adjustment or additional interventions

Given this close relationship, scientists have hoped that semaglutide and similar drugs that mimic the hormone GLP-1 (already approved to treat obesity and diabetes) could be an effective treatment for MASLD/MASH as well

For diabetic patients specifically, the combination of weight loss and blood sugar control may reduce or eliminate the need for medications beyond Metformin