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There are speculations that non-pathogenic commensal microorganisms, which co-evolved with humans, have been a source of immunomodulatory signals for the human body (the old friends hypothesis), and now prevent the development of immune-mediated chronic diseases (the hygiene hypothesis), with the proper composition of the microbiome promoting the maintenance of the bodys immune balance (the biodiversity hypothesis) [1, 39, 53, 54]

Ah Mew N, Cnaan A, McCarter R, Choi H, Glass P, Rice K, et al

Less supported scenario: If your B12 status is already normal, extra B12 has not been shown to consistently boost energy in otherwise healthy people

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A trained clinician can review your medical history, discuss any new symptoms, and order tests, such as blood work or imaging tests, to help pinpoint whats wrong