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44,45 Animal studies have shown significant reductions in A load in the early stages of AD following treatment with liraglutide, indicating a potential role in mitigating disease progression

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VvGST4 (A12M): VvGST4 _A12M_fw, VvGST4 _A12M_rv, VvGST4 (C13S): VvGST4_ C13S_fw, VvGST4 _C13S_rv, VvGST4 (N108H): VvGST4 _N108H_fw, VvGST4 _N108H_rv (Supplementary Table 4) using pANT20 as template

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R Whether natural sEH inhibitors (omega-3 fatty acids, specific flavonoids) can produce clinically meaningful EET preservation in humans at achievable dietary doses is not yet established