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Studies comparing rapid dose escalation to gradual low-dose initiation show that patients who begin low experience higher satisfaction and better medication adherence

The result is a metabolic environment where lean mass loss is likely unless protein intake is deliberately maintained and resistance training is consistently practiced

None of the clinical efficacy studies described below was conducted with JANUMET

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While genetic mouse models can reveal important insights into the mechanistic underpinnings of physiology and behavior, developmental and compensatory actions can occur, especially in relation to fundamental processes such as eating

Guglielmi G