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Significant differences between the two formulations were observed on days 5 and 7 ( p 0.0036), with a maximum circulatory B12 concentration of 454 3.9 pg/mL measured in the Sucrosomial B12 group compared to 274 11.1 pg/mL in the conventional Mecogen SL B12 group on day 5 (Figure 3 boxplots, bottom)

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Diagnosis typically involves blood tests including full blood count (showing macrocytosis), anti-intrinsic factor antibodies (which are specific for pernicious anaemia), and sometimes anti-parietal cell antibodies