inhibited glycolysis in lung fibroblasts by inhibiting 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 (PFKFB3) (206)
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Hypothalamic and gonadal components of hypogonadism in boys with Prader-Labhart- Willi syndrome
Reproductive toxicity studies of acetylcysteine solution in the rat given oral doses of acetylcysteine solution up to 1,000 mg/kg (5.2 times the human mucolytic dose) have also been reported in the literature.1 The only adverse effect observed was a slight non-dose-related reduction in fertility at dose levels of 500 or 1,000 mg/kg/day (2.6 or 5.2 times the human mucolytic dose) in the Segment I study