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Commercial insulin preparations differ in a number of ways, such as differences in the recombinant DNA production techniques, amino acid sequence, concentration, solubility, and the time of onset and duration of their biologic action

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2 This rapid growth has resulted in a brand prescription trend rate for these plans that is twice as high as those that do not offer weight loss coverage

The overall incidence of AEs was similar between oral semaglutide and comparators (approximately 6080% of patients in any subgroup had an AE) and, as expected, gastrointestinal AEs (primarily nausea, vomiting and diarrhoea) made up a substantial proportion of the overall events for oral semaglutide