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The liver is your body's primary detoxification organ, and it also happens to be the place where the highest concentration of glutathione is found

L.PetheS.LepoivreM.Danion-BougotR.et al (2000)

Visualization of ribonucleotide reductase catalytic oxidation establishes thioredoxins as its major reductants in yeast

For seniors with mild deficiencies, a standard oral supplement of 500 to 1,000 micrograms daily may be sufficient, as the body can only absorb a small percentage of B12 from supplements

& Wilson, P