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StatPearls [Internet], 2024 Jan Avinoam Shiran, Eric Remer, Ihab Asmer, Basheer Karkabi, Eran Zittan, Aliza Cassel, Mira Barak, Orit Rozenberg, Khaled Karkabi, Moshe Y Flugelman

Many patients report reduced discomfort or improved function within 1-2 weeks

Over a period of 6 months, patients lost an average of 12.8 kg, 11.3 kg, and 6.7 kg on the 1 mg, 0.5 mg, and 0.25 mg doses, respectively, as compared to a 2.2 kg weight loss in the placebo group [76]

Treatment reduces hepatic triglyceride content by more than 30%, normalizes transaminase levels, and markedly alleviates hepatic steatosis

Some researchers wrap vials in aluminum foil for additional protection

As a research compound, 5-Amino-1MQ has been studied in cellular biology and biochemical research literature examining NNMT (nicotinamide N-methyltransferase) enzyme inhibition, cellular nicotinamide metabolism, and methylation pathway research