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Furthermore, a preclinical study demonstrated that circulating MPs may impair brain function via immune-mediated vascular occlusion (Huang et al., 2025)

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NMO is mainly caused by auto-anti-AQP4 antibodies 282 that initially attack astrocytic endfeet, 283 leading to complement-mediated lysis and destruction of the glial limitans and astrocyte degeneration, which in turn cause the other pathophysiological sequalae (Fig

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"Guidelines for the diagnosis and treatment of cobalamin and folate disorders"

You may notice that dark spots and post-acne marks now have softer edges