Janku F, Claes B, Huang HJ, Falchook GS, Devogelaere B, Kockx M, Bempt IV, Reijans M, Naing A, Fu S, Piha-Paul SA, Hong DS, Holley VR, Tsimberidou AM, Stepanek VM, Patel SP, Kopetz ES , Subbiah V, Wheler JJ, Zinner RG, Karp DD, Luthra R, Roy-Chowdhuri S, Sablon E, Meric-Bernstam F, Maertens G, Kurzrock R
Peptide YY (PYY) Function: PYY is released postprandially from L-cells in the intestine and acts to reduce appetite
Losing 20 to 30 pounds on GLP-1 medications doesnt replace exercise, nutrition, sleep, and other healthy lifestyle changes
Establishing the cause of this insufficiency This is done by considering the following: Patient age (certain causes are more prevalent at certain ages) Other autoimmune disorders (indicates probability of an autoimmune cause) CT scan of adrenals CT or MRI scan of pituitary (if secondary / tertiary disease suspected) CXR (for suspected TB) Drugs Treatment There are different treatment protocols depending on the nature of the insufficiency
The drug's ability to mimic the effects of GLP-1, a hormone that regulates blood sugar and appetite, contributes to its efficacy
Protein pacing spreads daily protein intake across smaller meals, making it easier for people on GLP-1 medications to meet protein needs despite reduced appetite