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In the citric acid cycle, Vitamin B3 (Niacin) is involved in the formation of acetyl-CoA while conversion of its co-enzyme takes places from NAD+ (nicotinamide adenine dinucleotide) to NADH (12)

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The data was analyzed with FlowJo: median fluorescence emission at 525 nm from living, single cells was measured

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However, a clinical study reported that paclitaxel caused hypothyroidism in several patients, suggesting that paclitaxel can disrupt the hormonal balance (Mie, 2025)

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