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But more targets also equals more complexity, more potential side effects, and more unknowns about long-term safety

Furthermore, the nanoparticles were not retained in the lung over time (Supplementary Fig

Loss of the neurotransmitter dopamine, due to the degeneration of dopaminergic neurons in the midbrain underlies the pathophysiology of the motor dysfunction

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These structural variations may overlap with the types of complex chromosomal changes observed across neurodevelopmental disorders, such as Angelman and Prader-Willi syndromes, as well as single-gene disorders, including neurofibromatosis (NF1 and NF2) and tuberous sclerosis (TSC1 and TSC2) (154)