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We do not treat weight loss like it happens in a vacuum

Cost-effectiveness is not black and white, and accumulating data from real-world use could assist decision makers in making choices about coverage in the future

The Better Question to Bring to a Prescriber Instead of "can I try it for a month", ask what the plan is across the first six to twelve months, what would constitute an adequate trial of the medication, what would trigger stopping, and what the maintenance phase looks like if it works

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Redox Biol 71:103109 Gulati A, Jabbour A, Ismail TF, Guha K, Khwaja J, Raza S et al (2013) Association of fibrosis with mortality and sudden cardiac death in patients with nonischemic dilated cardiomyopathy

Human emotions emerge from complex overlapping circuits , not a single neurochemical switch