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Meet clinical BMI criteria and don't have contraindications: If you have a BMI 30 (or 27 with weight-related comorbidities like high blood pressure or type 2 diabetes), don't have a personal or family history of medullary thyroid carcinoma or MEN2, and don't have severe gastrointestinal disease or pancreatitis history, you may qualify clinically

Potential Research Applications: Melanocortin receptor binding and selectivity studies Pigmentation pathway and melanogenesis research -MSH analog comparative activity models Immune modulation and receptor interaction investigations For laboratory research only

GLP-1s (also called GLP-1 RASs), like Ozempic, have recently been shown to have potential mental health benefits, as well as physical benefits, and, whether we want to admit it or not, weight loss has a mental component

Gene expression analysis showed upregulation of survival pathways (Egr1, Akt1, Kras, Src, Foxo, Srf, VEGFR2, NOS1, NOS3) and downregulation of inflammatory mediators (NOS2, NFB)

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