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One of the more surprising findings of the present studies was the relatively small amount of d 3 -BB found in plasma compared with d 3 -TMAO after d 3 -l-carnitine challenge, especially after ex vivo fecal studies showed that BB is a major metabolite of l-carnitine produced by human fecal polymicrobial cultures (43)

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Mice were subcutaneously (SQ) administered either Veh, 30 nmol/kg RETA 32 , or 30 nmol/kg SEMA every other day before the initiation of the dark cycle at 5 pm

95% CI, -0.55% to -0.12%