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Hormonal and blood-sugar disruption, including elevated cortisol and prolactin, reduced insulin sensitivity, and hypoglycemia risk tied to IGF-1 receptor activity

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While it must be converted by the body into active coenzyme forms, its unique molecular structure makes it incredibly valuable in its own right

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In vitro assays using BaF-BO3 cells transfected with the hGH receptor confirmed that AOD9604 does not compete for the hGH receptor and does not induce cell proliferation unlike intact hGH establishing that it operates via a novel mechanism distinct from traditional hGH-stimulated pathways

Using various techniques, we investigated its effects on weight loss and underlying neuronal mechanisms in mice and rats