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doi: 10.1016/j.neurobiolaging.2014.03.040

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Reported side effects are generally mild and may include injection site irritation, headache, or transient fatigue

B12 from food and supplements has to pass through a fairly involved process in the stomach and gut before your body can use it, and that process becomes less efficient with age, with certain medications, and with diets that include little or no animal protein

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