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1 Introduction The pathophysiology of post-traumatic stress disorder (PTSD) is highly complex, and PTSD remains a largely underdiagnosed and undertreated mood disorder ( First-line pharmacologic treatments include selective serotonin reuptake inhibitors (i.e., sertraline, paroxetine), which are the only FDA-approved drugs for this condition ( The lack of reliable biomarkers makes diagnosis, as well as developing more efficacious treatments, difficult ( At the cellular level, PTSD has been associated with dysregulated neurotransmitter signaling and inflammatory response ( 2+ ions, thereby creating a vicious cycle in which ROS enhance cytosolic Ca 2+ levels, and Ca 2+ enhances ROS production, which may worsen PTSD symptoms
Advanced Biomaterials for Regulating Polarization of Macrophages in Wound Healing
Airway hyperreactivity, a cardinal feature of allergic airways disease, was also measured
Wound dressing: from nanomaterials to diagnostic dressings and healing evaluations
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