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Similarly, MYC binds directly to the promoter elements of glutamine transporters such as ASCT2 and SN2 in T cells to promote their mRNA synthesis, thereby increasing glutamine uptake and metabolism and supporting the activation and functional maintenance of immune cells [17]

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Nat Rev Endocrinol (2010) 6(5):2513.10.1038/nrendo.2010.43 291 ShaletSMClaytonPEPriceDA