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Still, long-term human data on multi-peptide stacks remains limited, and that uncertainty should be respected

Mechanistic sub-study embedded in an efficacy trial + Incorporate GSM/dryness endpoints (validated questionnaires, clinician assessment, pH) into semaglutide RCTs or pragmatic trials, with pre-specified subgroup analyses by menopausal status and HRT use

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In summary, a promoting role of anti-TSHR antibodies on breast cancer has been shown, while the role of anti-Tg and anti-TPO is unclear