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132 WongJ

doi: 10.3389/fnint.2020.00016 14

Granulocyte-macrophage colony-stimulating factor preferentially activates the 94-kD STAT5A and an 80-kD STAT5A isoform in human peripheral blood monocytes

Two studies from two different institutions recently identified a novel iron death signaling pathway independent of GPX4 (Bersuker et al., 2019

doi: 10.1126/science.1124147

LP-BM5-infected mice treatment with GSH replacement changed the macrophage polarization to M1 profile, inducing an increase in Th1 cytokine production and augmented antiviral response [38]