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It is a limitation, nonetheless larger studies with a sufficient number of patients are required to confirm that clonidine (or other -agonist) should be used in the withdrawal phase in patients treated with opioid with cancer pain, not only in those with addiction

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While that study did not report runaway tumor growth either, the lack of a spectacular reduction in tumor size, suggests BPC-157 offers no anti-cancer benefit and it leaves open the worry that it could even accelerate malignancy under the right conditions

In conclusion, LCS3 is a potent and reversible inhibitor of GSR and TXNRD1 with anti-tumor activity

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