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Although TA could form multiple hydrogen bonds with PMI, single or double hydrogen bonds could still be formed with relatively weak interaction, which could be easily broken and lead to free TA release

Molecular profiling data have greatly facilitated the identification of candidate gene driver alterations in GC, such as gene mutations, chromosomal alterations, transcriptional changes, and dysregulated epigenetic modifications 2,3

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Large body-composition outcome trials are lacking