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Other novel GLP-1RAs have also been tested, whether used singly or in combination with other drugs

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In the SURPASS clinical trial program for type 2 diabetes, patients achieved HbA1c reductions of 1.9% to 2.6% depending on dose, with weight loss averaging 15-22 pounds across studies

For people with type 2 diabetes, lower BMI thresholds may apply (30 kg/m) as outlined in NICE guidance

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