Weight loss reduces the mechanical load on bones, which can lead to lower bone density and, in some people such as those who are postmenopausal, as well as people over age 65 an increased risk of fracture
doi: 10.1080/14740338.2018.1428305 [DOI] [PubMed] [Google Scholar] 230.Zafer M, Tavaglione F, Romero-Gmez M, et al
When used in addition to lifestyle interventions, 2.4 mg of semaglutide once weekly resulted in an average weight loss of 15 percent
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But coverage of weight loss treatments is less widespread, and navigating the complex insurance landscape can be challenging for patients and time consuming for doctors who prescribe the medications
EASL-EASD-EASO clinical practice guidelines on the management of metabolic dysfunction-associated steatotic liver disease (MASLD)