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It upregulates the expression of vascular endothelial growth factor (VEGF), epidermal growth factor (EGF), and their respective receptors at sites of injury, directly promoting angiogenesis and epithelial repair

The skin then produces excess melanin in those areas as part of the healing process, resulting in dark spots known as post-inflammatory hyperpigmentation

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However, it was later determined that LA is biosynthesized by animals

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Despite this biochemical connection, the two compounds serve distinct functions in clinical nutrition and metabolic health applications