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While iron deficiencies are common, more than half of all cases are undiagnosed

The large-scale STEP clinical trials (Semaglutide Treatment Effect in People with Obesity), published in the New England Journal of Medicine and JAMA, did not report increased cold sensitivity as a significant adverse effect

Acarbose alters bile acid metabolism through changes in gut microbial populations (192)

However, not everyone experiences cold sensitivitysome patients lose significant weight without this side effect at all

Im thrilled by studies that make GLP-1 therapies seem like holy water drawn from the fountain of youth