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Subsequently, the team further found that intrathecal administration of SM has demonstrated potent, dose-dependent, and long-lasting anti-allodynic effects in neuropathic pain models induced by spinal nerve injury [72]

Although clinical outcomes have varied, with some showing reductions in albuminuria and others failing to meet primary endpoints, their collective results reinforce the biological relevance of these pathways and justify continued therapeutic exploration

Key Takeaway: Your body often needs an adjustment period to balance the bacteria in your gut