Finally, previous research has shown there may be sex differences in the rate of people who experience side effects, however we did not explore differences in discontinuation reasons by sex
You know, uh, I think that's a really great point because I talk to orthos every day and, uh, it's one of the most misunderstood aspects that, that orthos have, which is that they feel that their technology is their differentiator
In the definitive SURMOUNT-5 head-to-head trial (NEJM 2025), tirzepatide produced ~20% weight loss vs
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Different Dual Approaches# Weight Loss Comparison# Cross-trial comparison is limited by differences in population, duration, dose escalation, and trial design