Among 236 registered patients with T2DM, whose glycemic hemoglobin higher than 6.5% within 3 months, screened at our outpatient clinic, 102 subjects met the following criteria were enrolled: (1) age between 20 and 65 years, (2) diagnosis of type 2 diabetes for more than one year, (3) body mass index (BMI) 18 kg/m2 and 30 kg/m2, (4) fasting triglyceride 150 mg/dl or fasting low-density-lipoprotein cholesterol (LDL) 100 mg/dl and (5) willing to participate in and fill out questionnaires for this trial
500
Its potential benefit has been posited due to its effect on improving mitochondrial function and the benefit seen as a neuroprotective agent in other clinical situations such as ischemic stroke, neurodegenerative diseases, and chemotherapy-induced encephalopathy.13 The authors of one article posited 2-3mg/kg/day divided into three doses for 7-10 days for newly infected patients could be a reasonable dose for initial studies.14 Given one meta-analysis reported that 12-35% of patients with long COVID suffered from cognitive impairment (colloquially called brain fog) and another found elevated brain injury markers during the acute phase of COVID-19, potential treatment and management strategies are in demand.13,14,15 Currently there are some trials evaluating the use of methylene blue for COVID-19, though, results and outcomes are not yet available.16,17 Brain injury and traumatic brain injury continue to be significant sources of morbidity and mortality and effective treatment options for prevention of acute and long-term damage are needed
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Eating smaller, bland meals and staying hydrated helps manage nausea without stopping the medication
This slows down digestion, lowers blood sugar, and makes you feel full
