10.1196/annals.1320.003 Ann N Y Acad Sci
Unexplained increases in blood glucose readings, return of diabetes symptoms (increased thirst, frequent urination, fatigue), or sudden changes in appetite and weight loss patterns may suggest reduced medication potency
The appeal of novel weight-loss compounds is understandable, but the risks of self-administering unlicensed injectables without medical oversight are substantial and should not be underestimated
Common signs that a dose may be too high or increased too quickly include: Persistent nausea that does not improve with time
Probably, as a relatively small protein without multi-domains, its unfolding followed a simple path, and it remained active until heat-induced aggregation
GLP-1 receptor agonists lower HbA1c by 11.5% but this may be dependent of the type of GLP-1 receptor agonist prescribed, the dosage, baseline HbA1c levels and glucose-lowering co-medication [24]