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When used as a monotherapymeaning its taken on its own, without being combined with other medicationsits currently being tested in a large phase 3 clinical trial program called RENEW

Sphingolipids in neutrophil function and inflammatory responses: mechanisms and implications for intestinal immunity and inflammation in ulcerative colitis

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R NAT2 polymorphisms alter catalytic activity primarily through effects on protein stability and degradation rates rather than changes to the active site itself (slow acetylator alleles produce unstable protein that is rapidly ubiquitinated and degraded)