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A plan that excludes weight loss coverage may still cover the same molecule for a different approved use, such as tirzepatide for moderate to severe obstructive sleep apnea in adults with obesity, or semaglutide for cardiovascular risk reduction in adults with established cardiovascular disease

This has led to speculation that GLP-2 may act indirectly on bone cells in humans, with the presence of GLP-2R on the parathyroid gland suggesting a potential link between GLP-2, PTH secretion, and bone turnover

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10.1097/01.ALC.0000098873.80433.BA 251 SchroederJ

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However, pretreatment with 10 M GHK-Cu significantly reduced the secretion of both TNF- and IL-6 to much lower levels, confirming its anti-inflammatory properties