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Epub 2017 Jan 16

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Tirzepatide is a dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist approved by the FDA for type 2 diabetes management under the brand name Mounjaro and for chronic weight management as Zepbound

The saturated fats common in the Western diet are also associated with increases in inflammation by the nuclear factor kappa B (NF-B) pathway and NLRP3 inflammasome, possibly contributing to obesity, as reviewed by Las Heras et al

40 Subsequently, researchers demonstrated that siRNA could be tailored to disrupt the expression of any pathogenic gene, propelling RNAi into the spotlight and fostering its active application in the treatment of various diseases

As a result, it supports muscle recovery and nutrient utilization without relying on direct hormonal stimulation