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The impact of continuous positive airway pressure therapy on cardiovascular events in patients with obstructive sleep apnoea: an updated systematic review and meta-analysis

Conforti L, Gilley J, Coleman MP

Although adverse events were observed, this was a study population with advanced cancer disease, many of whom had exhausted other lines of treatment and all of whom were taking other medication at the time of the study, and therefore these events may not be generalisable to other populations

Empagliflozin reduced mortality and hospitalization for heart failure across the spectrum of cardiovascular risk in the EMPA-REG OUTCOME trial

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Therefore, to minimize risks of discolouration, choose products approved by dermatologists, follow usage instructions carefully, and perform a patch test before applying to the face or sensitive areas