Glucagon-like peptide receptor agonists (GLP-1 RAs or GLP-1 agonists for short) are drugs manufactured to bind to GLP-1 receptors, essentially mimicking and magnifying the effects of these hormones
STAT News cited a recently published British Medical Journal review of 37 studies, tallying an aggregate of more than 9,300 participants, in which approximately 50% of the people who started on the drugs stop taking them within one year
The GIP receptor activation brings its own party tricks to the table, improving insulin sensitivity and potentially enhancing fat metabolism in ways that GLP-1 alone cannot achieve
"With adding the pharmacology of glucagon, we might get very close to the amount of weight loss one should aspire to," he said
A randomized phase 2b trial examined the effects of the glucagon-like peptide-1 and glucagon receptor agonist cotadutide on kidney outcomes in patients with diabetic kidney disease
Start by swapping one staple, such as white bread or white rice, for a whole-grain alternative like brown rice, wheat-based pasta, a few times a week
