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Arachidonic acid metabolism was most prominently affected, with upregulation of prostaglandins and leukotrienes suggesting active inflammatory signaling in the pathophysiology of MMA [61]

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In summary, the neuroprotective effects of GLP-1RAs have been demonstrated in various in vivo models of diabetes, aging, AD, and PD

The parasitized cells were distributed in 96-well plates that were preloaded with ten concentrations in multiples of two MB (0.1 to 51.2 nM) or chloroquine (CQ) as the positive control (1.95 to 1,000 nM), as well as the vehicle as a negative control