Endocrinology 148 , 12061217 (2007)
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Notably, these mechanisms not only collectively safeguard cutaneous structural and immunological integrity, but also orchestrate a dynamic regulatory network in response to exogenous stimuli (e.g., UV radiation, oxidative stress) and endogenous inflammation
The pathogens in question were the bacterium Staphylococcus aureus and the fungus Candida albicans , which together account for nearly 150,000 infections and tens of thousands of deaths in the United States every year.13 14 The researchers found that even very small concentrations of the peptide not only killed significant amounts of these pathogens but also reduced their viability