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Beginners often start on the lower end (around 100-200 mg) to assess tolerance, then may increase to higher doses (500+ mg) in later sessions

GLP-1 therapy also slows the digestive process, allowing more gradual absorption of food

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Animal reproduction studies with semaglutide have shown embryofetal toxicity, including structural abnormalities, at exposures below those expected at therapeutic doses in humans

Brandt SJ, Gotz A, Tschop MH, Muller TD